Decoding the neural architecture of behavior.
You've got the data. Maybe you spent three months injecting the right construct, raising your larvae to 6 days post-fertilization, mounting them in agarose, and finally pulling clean two-photon stacks through…
A mechanical lesion in a three-day-old zebrafish larva closes within roughly forty-eight hours. Within several days…
Many mammalian olfactory receptors do not fail in a heterologous assay because their ligand is unknown or their…
You can have a beautiful transgenic line, a healthy clutch, and a perfectly aligned light path—and still get the wrong…
A science-art exhibit can close the baseline interest gap between STEM and non-STEM adults in a single visit. That…
A zebrafish behavior assay can produce thousands of frames in a single session, but raw video is not yet a measurement…
Your larval zebrafish are swimming, the stimulus streams look beautifully separated, and the tracking software is…
You have a spinal cord roughly 300 microns wide. It contains hundreds of interneuron subtypes making thousands of…
Neural data does not arrive in a form that music can immediately understand. An EEG trace is a changing voltage…
Your calcium movie looks clean until you ask the uncomfortable question: are those neural signals from the larva, or…
A single odorant molecule contacting an olfactory sensory neuron does not enter a clean relay. It enters a sequence of…
Neuronal migration is not a quiet relocation from one point in the brain to another. It is a sequence of decisions made…
A brain wave music project usually fails before the first note plays. The headset loses contact, the signal fills with…
A confocal stack can look perfect and still be analytically unusable. Fluorescent reporters are firing across the optic…
Detecting olfactory receptors outside the olfactory epithelium is less like finding a bright signal than like…
You're staring down the scope at a perfectly prepped stripe assay — alternating lanes of netrin-1 and BSA, your…
A 22% drop in salivary cortisol. A 30% reduction in interleukin-6. A 28% decline in TNF-alpha. These are not…
Brain data has a shape problem. The electrical chatter of neurons — the slow drift of cortical oscillations, the crisp…
You can have a beautiful zebrafish brain movie, a stable preparation, and a perfectly healthy-looking larva—and still…
A single bolus of capsaicin injected into deep craniofacial tissue drops the mechanical activation threshold of…
The habenulo-interpeduncular pathway is a compact tract with an unusually large interpretive burden. In zebrafish, the…
A light-sheet zebrafish brain protocol can fail before the microscope ever starts collecting data. The usual culprit is…
A larval zebrafish can discriminate between two chemical cues delivered 100 µm apart—across paired nasal cavities…
A range of 80 to 97 percent. That is the decline in insect populations represented by a prominent ecological…
During a fast volumetric calcium scan, a larval zebrafish twitches — a reflex adjustment, a momentary flex in a quiet…
You've pulled the fish out of the tank, you've pipetted what should be a perfect bolus of indicator into the naris…
You can record calcium activity across the entire larval brain. That part is solved. The harder problem is assigning…